Does Metformin Cause Weight Loss? What to know Before you take It

Does Metformin Cause Weight Loss? What to know Before you take It #weightloss


Struggling to lose weight? metformin will do over facilitate management your glucose — it's going to additionally assist you lose stubborn pounds. Here’s what you would like to grasp concerning metformin and weight loss.
Although metformin will cause weight loss, it’s still necessary to eat healthy and exercise often to stay weight you’ve lost off.
Darren Lehane/Alamy

If you’re managing kind two polygenic disorder with metformin (Glucophage), you may be at home with unwanted facet effects of this drug — specifically, stomach upset, diarrhea, muscle aches, and temporary state. These are often a figurative and literal pain, however you may welcome one facet impact of Glucophage with open arms, notably if you’ve struggled to slim down.

Metformin isn’t a weight loss drug, however researchers have found a link between the drug and weight loss. In fact, a long-run study revealed in Apr 2012 within the journal polygenic disorder Care that was conducted by the polygenic disorder hindrance Program (DPP) complete that the drug may function a treatment for excess weight, though additional studies area unit required.
What Is Glucophage and the way will It Work?

“[Metformin] has been thought-about a first-line medication within the treatment of kind two polygenic disorder, and it chiefly acts by lowering the number of aldohexose discharged by the liver,” says Minisha Sood, MD, associate degree specialist at Lenox Hill Hospital in ny town. “It additionally helps a endocrine known as hypoglycemic agent to figure higher by serving to muscles use aldohexose in a very additional economical manner. once hypoglycemic agent works higher (and hypoglycemic agent sensitivity improves), a person’s hypoglycemic agent levels area unit below they'd be otherwise.”

There’s no cure for kind two polygenic disorder, however the correct combination of medication and healthy fashion will stabilize glucose levels, which, of course, is that the finish goal of any polygenic disorder treatment.

As the medication helps your body properly metabolise food and restores your ability to retort to hypoglycemic agent, you’ll not solely feel higher, you'll doubtless avoid complications of high glucose, like cardiopathy, excretory organ harm, nerve harm (diabetic neuropathy), and eye harm (retinopathy).
Why will Glucophage Cause Weight Loss?

The relationship between Glucophage and weight is unclear, however many theories offer a plausible clarification for weight fluctuations. Reduced hunger is one proved facet impact of Glucophage, in keeping with the salad dressing Clinic. it would not seem as if you’re uptake less with this drug, however the quantity of calories you’re presently overwhelming for breakfast, lunch, and dinner can be below your traditional food intake. This refined amendment in craving may well be accountable for a gradual decline in weight.

Having a frequent stomach upset or looseness of the bowels, that is another facet impact of the drug, also can have an effect on your food intake.

“Temporary epithelial duct upset (typically full-fledged at the start of treatment) from taking Glucophage may additionally play a task in weight loss,” says Suzanne Magnotta, RD, CDE, vp of clinical services for Achieving higher management in Conshohocken, Pennsylvania.

Gastrointestinal symptoms common with this drug embrace abdomen pain, diarrhea, and nausea. Discomfort are often therefore severe that you simply might not want uptake a lot of, and later consume fewer calories.
Is long-run Weight Loss doable on Metformin?

Even though Glucophage will assist you shed pounds, the number you lose can be so much but expected. On average, weight loss when one year on the drug is just vi pounds, in keeping with the Apr 2012 polygenic disorder Care study.

So whereas Glucophage is usually given to individuals with high hypoglycemic agent levels WHO have problem losing weight, it’s not a miracle weight loss answer, says Dr. Sood. In alternative words, don’t expect a dramatic amendment in weight if you eat and lead a inactive life. you want to follow a wise weight loss set up with healthy uptake and physical activity to check any important amendment in weight.

“If somebody isn’t following healthy habits, then taking Glucophage won't end in weight loss,” she says. “It’s necessary to follow a healthy diet low in refined sugars and carbohydrates if vulnerable to high hypoglycemic agent levels, so most have the benefit of the medication is received.”

Keep in mind that whereas the quantity on the size may drop whereas taking this medication, this weight loss is also temporary. you may regain pounds once you stop taking the drug and your craving returns to traditional, thus the importance of jutting with a healthy fashion.

If you’re considering taking Glucophage with a weight loss medication, raise your doctor for recommendations. this mixture may assist you lose and chase away extra pounds, though there’s very little to no test knowledge to support this claim, says Sood.
Can individuals while not polygenic disorder Take Metformin?

What if you don’t have kind two diabetes? are you able to still take Glucophage for weight loss? this can be a wonderful question, and also the short answer is affirmative. Sood explains that Glucophage has been used off-label (or outside its meant purpose) for weight management. however since this drug is just obtainable by prescription and hasn’t been approved for weight loss by the Federal Drug Administration (FDA), your doctor may 1st suggest ancient methods for weight loss.

For example:
  • Avoid sweet drinks.
  • Drink water before meals to fill your abdomen so you eat less.
  • Exercise for half-hour most days of the week.
  • Prepare whole foods, such fruits, vegetables, and grains.
  • Limit intake of processed foods.
  • Eat a high-protein, low-carb, diet.
  • apply portion management.


If you don’t have kind two polygenic disorder, your doctor could exit on this drug if you’re rotund and troubled to slim down. But again, Glucophage isn’t a substitute for healthy uptake and regular exercise, that area unit keys to property weight loss. These habits additionally encourage weight loss if you've got kind two polygenic disorder however can’t take Glucophage.

"For those patients with polygenic disorder WHO cannot take Glucophage, because of chronic nephropathy or alternative issues, diet and fashion modifications can still be of utmost importance, whether or not they’re prescribed alternate medication or not. dominant sugar intake, increasing physical activity, and managing stress is that the cornerstone of up glycemic management,” says Magnotta.

“Make it some extent to face up each hour some and walk round the space, the yard, or the block. very little bits of physical activity over the day add up, leading to the burning of additional calories as a result.”

The Bottom Line on Glucophage and Weight Loss




All things thought-about, Glucophage will cause a modest reduction in weight, possibly because of facet effects, sort of a shrivelled craving associate degreed an stomach upset. however though effective for weight loss, the drug doesn’t replace ancient diet ways. therefore if you’re trying to lose additional and keep the load off longer, you've got to urge active and eat right.

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